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名稱	PTH 1-34 ELISA Kit
型號
更新時間	2023-09-25
特點	PTH 1-34 ELISA Kit is intended for research use only in the qualitative detection of antibodies to human PTH (1-34) in humans or other animal models.}

詳細內(nèi)容

一.產(chǎn)品名稱：

通用名稱：甲狀旁腺激素1-34 ELISA試劑盒

英文名稱：PTH 1-34 ELISA Kit

二.PTH 1-34 ELISA Kit介紹：

Teriparatide (rhPTH 1-34) is a recombinant human parathyroid hormone derivative consisting of the first 34 amino acids of the hormone. Teriparatide was approved as a drug by the FDA in 2002 and is sold by Eli Lilly & Co. under the brand name Forteo. Teriparatide is indicated for use in patients with osteoporosis. It is currently administered by injection and has an anabolic effect on bone, binding to the PTH/PTHrp Type 1 receptor with the same affinity as the intact molecule, PTH (1-84). This receptor activation results in a series of events leading to the formation of new trabecular and cortical bone. Research is continuing at pharmaceutical and biotech companies to pursue similar drugs and alternate delivery pathways.
Immunogenicity for this drug, defined as the presence of antibodies to human PTH (1-34), was detected in 2.8% of women receiving teriparatide during the clinical trials of Forteo. The detection of these
circulating antibodies may be of clinical relevance for the proper assessment of patients.

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